Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443443 | 0.91 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6445687 | 0.91 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6443325 | 0.91 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6446350 | 0.91 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL218830 | 0.85 | TP53 (0.38) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL218229 | 0.74 | — | — | |
| SCHEMBL16207443 | 0.66 | — | — | |
| Biphenyl SCHEMBL5868585 | 0.66 | ALDH1A1 (0.56) | LTA4HPCSK9PTGS2SMN1; SMN2TP53 | |
| Biphenyl SCHEMBL15347228 | 0.66 | ALDH1A1 (0.56) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| Toluene SCHEMBL6257976 | 0.64 | TSHR (0.65) | LTA4HPCSK9CES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858164-B2 | Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium | RICOH COMPANY LIMITED (JP) | 2005-02-22 | — | — | US | disclosed |
| US-5907382-A | Transparent conductive substrate and display apparatus | KABUSHIKI KAISHA TOSHIBA (JP) | 1999-05-25 | — | — | US | disclosed |
| US-4668666-A | INSECTICIDES | ADAMS VETERINARY RESEARCH LABORATORIES (US) | 1987-05-26 | — | — | US | disclosed |
| WO-1986003374-A1 | LONG-ACTING PYRETHRUM/PYRETHROID BASED PESTICIDES WITH SILICONE STABILIZERS | ADAMS VETERINARY RESEARCH LABORATORIES, INC. (US) | 1986-06-19 | — | — | WO | disclosed |