SCHEMBL218830

SCHEMBL218830

CCC[Si]c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
SIGMAR1 Q99720 1/20 0.33
PSIP1 O75475 1/20 0.32
CA4 P22748 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
PCSK9 Q8NBP7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
LTA4H P09960 1/20 0.31
LMNA P02545 3/20 0.31
TAAR1 Q96RJ0 2/20 0.31
ATM Q13315 1/20 0.31
SLC6A2 P23975 1/20 0.31
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6439636 0.85 LTA4H (0.38) TP53SIGMAR1CES2CES1PCSK9
SCHEMBL6443443 0.81 DNM1 (0.40) TP53SIGMAR1CES2CES1ALDH1A1
SCHEMBL6446350 0.81 DNM1 (0.40) TP53SIGMAR1CES2CES1ALDH1A1
SCHEMBL6443325 0.81 DNM1 (0.40) TP53SIGMAR1CES2CES1ALDH1A1
SCHEMBL6445687 0.81 DNM1 (0.40) TP53SIGMAR1CES2CES1ALDH1A1
SCHEMBL218229 0.78
SCHEMBL16207443 0.69
SCHEMBL16207361 0.67
Biphenyl SCHEMBL967556 0.61 ALDH1A1 (0.64) TP53KDM4EALDH1A1HPGDTAAR1
SCHEMBL74571 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
US-8748361-B2 Polyalpha-olefin compositions and processes to produce the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-06-10 US disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
EP-1519389-A1 Electrically insulative powder coatings and compositions and methods for making them ROHM AND HAAS COMPANY (US) 2005-03-30 EP disclosed
US-20050065294-A1 Electrically insulative powder coatings and compositions and methods for making them CRAMER MICHELE LE (US) 2005-03-24 US disclosed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US disclosed
EP-1337536-A1 CATIONIC GROUP-3 CATALYST SYSTEM ExxonMobil Chemical Patents Inc. (US) 2003-08-27 EP disclosed
WO-2002032909-A1 CATIONIC GROUP-3 CATALYST SYSTEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-04-25 WO disclosed
US-5907382-A Transparent conductive substrate and display apparatus KABUSHIKI KAISHA TOSHIBA (JP) 1999-05-25 US disclosed
US-5112710-A ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD SEIKO EPSON CORPORATION (JP) 1992-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 TP53 3961/4885SIGMAR1 1617/4885PSIP1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.