Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439680 | 0.93 | HTR6 (0.41) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL6439371 | 0.91 | PTGDR2 (0.43) | PTGDR2PTGDRHTR6NOD2NOD1 | |
| SCHEMBL6436468 | 0.89 | PTGDR (0.45) | PTGDR2PTGDRHTR6NOD2NOD1 | |
| SCHEMBL3563498 | 0.85 | HTR6 (0.48) | PTGDR2PTGDRHTR6CYP3A4CYP2D6 | |
| SCHEMBL6435967 | 0.84 | HTR6 (0.54) | PTGDR2PTGDRHTR6NOD2NOD1 | |
| SCHEMBL6526507 | 0.81 | LMNA (0.47) | HTR6LMNA | |
| SCHEMBL6440894 | 0.80 | PTGDR2 (0.47) | PTGDR2PTGDRHTR6NOD2NOD1 | |
| SCHEMBL6439590 | 0.80 | HTR6 (0.43) | HTR6CYP3A4CYP2D6LMNA | |
| SCHEMBL6440512 | 0.79 | PTGDR2 (0.48) | PTGDR2PTGDRHTR6NOD2NOD1 | |
| SCHEMBL6441972 | 0.78 | HTR6 (0.43) | PTGDR2PTGDRHTR6NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |