Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773726 | 0.89 | TBXAS1 (0.42) | TBXAS1TAAR1GAASMN1; SMN2HTR1A | |
| SCHEMBL10775474 | 0.86 | TBXAS1 (0.40) | TBXAS1TAAR1GAASMN1; SMN2KDM4E | |
| SCHEMBL10774871 | 0.81 | TBXAS1 (0.53) | TBXAS1TAAR1GAASMN1; SMN2HTR1A | |
| SCHEMBL8068178 | 0.78 | ALOX5 (0.32) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL10775884 | 0.69 | TBXAS1 (0.53) | TBXAS1TAAR1 | |
| SCHEMBL10777505 | 0.68 | TBXAS1 (0.40) | TBXAS1TAAR1GAASMN1; SMN2KDM4E | |
| SCHEMBL9835155 | 0.68 | TBXAS1 (0.79) | TBXAS1GAA | |
| SCHEMBL10772872 | 0.65 | TBXAS1 (0.42) | TBXAS1GAASMN1; SMN2HTTROCK2 | |
| SCHEMBL10548966 | 0.63 | MEN1 (0.45) | TBXAS1 | |
| SCHEMBL9835663 | 0.61 | TBXAS1 (0.43) | TBXAS1GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7223955-A | — | — | None | — | — | JP | disclosed |
| US-20050222193-A1 | Novel combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-10-06 | — | — | US | disclosed |
| WO-2005074932-A1 | THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-20050165041-A1 | Combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-07-28 | — | — | US | disclosed |
| EP-1517706-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA Pharma AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| EP-1506016-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA Pharma AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094967-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| JP-H07223955-A | AGENT FOR TREATMENT AND PREVENTION OF DIABETIC COMPLICATION | SANKYO CO LTD | 1995-08-22 | — | — | JP | disclosed |