Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 10/20 | 0.32 |
| ▸ | CA9 | Q16790 | 10/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775514 | 0.86 | TBXAS1 (0.40) | TBXAS1KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL10775474 | 0.78 | TBXAS1 (0.40) | TBXAS1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9836779 | 0.78 | TBXAS1 (0.76) | TBXAS1KDM4ENPC1 | |
| SCHEMBL9835838 | 0.78 | KDM4E (0.35) | TBXAS1KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9836723 | 0.78 | KDM4E (0.39) | TBXAS1KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9835184 | 0.77 | TBXAS1 (0.61) | TBXAS1KDM4EALDH1A1MAPK1GAA | |
| SCHEMBL9836524 | 0.77 | TBXAS1 (0.43) | TBXAS1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL9836618 | 0.73 | ALDH1A1 (0.45) | KDM4EHPGDL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL7595087 | 0.71 | CNR2 (0.38) | KDM4EHPGDL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL9835177 | 0.69 | TBXAS1 (0.53) | TBXAS1KDM4EL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |