Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.79 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837297 | 0.90 | TBXAS1 (0.64) | TBXAS1EGLN3ALDH1A1GAA | |
| Imitrodast SCHEMBL166460 | 0.88 | TBXAS1 (1.00) | TBXAS1 | |
| Imitrodast SCHEMBL99497 | 0.87 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL9835184 | 0.87 | TBXAS1 (0.61) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9837516 | 0.86 | TBXAS1 (0.59) | TBXAS1EGLN3ALDH1A1GAA | |
| SCHEMBL9837324 | 0.82 | TBXAS1 (1.00) | TBXAS1EGLN3ALDH1A1GAA | |
| SCHEMBL9834831 | 0.80 | TBXAS1 (0.69) | TBXAS1ALDH1A1GAA | |
| Imitrodast SCHEMBL8156405 | 0.78 | TBXAS1 (0.81) | TBXAS1ALDH1A1 | |
| SCHEMBL9836779 | 0.76 | TBXAS1 (0.76) | TBXAS1 | |
| Imitrodast SCHEMBL1794449 | 0.75 | TBXAS1 (0.71) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1023013-C | Process for preparing thianaphthene derivatives | SANKYO CO (JP) | 1993-12-08 | — | — | CN | claimed |
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | claimed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | claimed |
| CN-87102672-A | Thioindol derivatives, process for their preparation and their use | — | 1987-11-04 | — | — | CN | claimed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | claimed |