Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439051 | 1.00 | LMNA (0.32) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL11610305 | 0.81 | LMNA (0.35) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL6439208 | 0.77 | ALDH1A1 (0.40) | LMNABLMPMP22MAPTKMT2A | |
| SCHEMBL31287885 | 0.77 | LMNA (0.32) | LMNAALOX15BLMPMP22 | |
| SCHEMBL6437798 | 0.77 | ALDH1A1 (0.40) | LMNABLMPMP22MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL19900734 | 0.74 | ALDH1A1 (0.38) | LMNABLMPMP22MAPT | |
| Hydrochloric Acid SCHEMBL19900732 | 0.74 | ALDH1A1 (0.38) | LMNABLMPMP22MAPT | |
| Hydrochloric Acid SCHEMBL19900791 | 0.74 | ALDH1A1 (0.38) | LMNABLMPMP22MAPT | |
| SCHEMBL622355 | 0.74 | — | — | |
| SCHEMBL435447 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155138-B1 | METHOD FOR PREPARING OPTICALLY ACTIVE 3,3,3-TRIFLUOROMETHYL-2-ALKYL PROPIONIC ACID DERIVATIVES | LONZA AG (CH) | 2005-01-05 | — | — | EP | claimed |
| EP-1155138-B1 | METHOD FOR PREPARING OPTICALLY ACTIVE 3,3,3-TRIFLUOROMETHYL-2-ALKYL PROPIONIC ACID DERIVATIVES | LONZA AG (CH) | 2005-01-05 | — | — | EP | disclosed |
| US-6599721-B2 | Chemical intermediates; hydrolysis using hydrolases | LONZA AG (CH) | 2003-07-29 | — | — | US | disclosed |