Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.63 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234654 | 0.89 | GPR35 (0.51) | GPR35TRPM4KDM4ELMNAHTT | |
| SCHEMBL9495180 | 0.81 | GPR35 (0.58) | GPR35TRPM4LMNAHTTTSHR | |
| SCHEMBL9495162 | 0.79 | GPR35 (0.63) | GPR35TRPM4KDM4EMAPTTSHR | |
| Acreozast SCHEMBL6454819 | 0.79 | GPR35 (0.59) | GPR35TRPM4ALDH1A1 | |
| Lodoxamide SCHEMBL119881 | 0.77 | GPR35 (1.00) | GPR35LMNAHTTMAPTTSHR | |
| SCHEMBL11703780 | 0.76 | GPR35 (0.63) | GPR35LMNAHTTMAPTTSHR | |
| SCHEMBL10339385 | 0.76 | GPR35 (0.53) | GPR35TRPM4LMNAMAPTMEN1 | |
| SCHEMBL9495446 | 0.76 | GPR35 (0.60) | GPR35TRPM4LMNAMAPTMEN1 | |
| Lodoxamide SCHEMBL3141058 | 0.76 | GPR35 (0.97) | GPR35LMNAHTTMAPTTSHR | |
| SCHEMBL10335283 | 0.74 | GPR35 (0.54) | GPR35LMNAHTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | claimed |
| US-4912135-A | Benzene ring with amido substitutions in position 1 and 3 | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0315112-A2 | Novel amide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1989-05-10 | — | — | EP | claimed |
| WO-2005074932-A1 | THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | disclosed |
| EP-1517706-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA Pharma AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| EP-1506016-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA Pharma AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094967-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4912135-A | Benzene ring with amido substitutions in position 1 and 3 | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0315112-A2 | Novel amide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1989-05-10 | — | — | EP | disclosed |