Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218614 | 0.84 | MAPT (0.33) | LMNAMAPK1SMN1; SMN2CES2CES1 | |
| SCHEMBL8309821 | 0.78 | MEN1 (0.33) | LMNAMAPK1SMN1; SMN2KMT2AMEP1B | |
| SCHEMBL6445788 | 0.75 | CES2 (0.38) | LMNAMAPK1SMN1; SMN2CES2CES1 | |
| SCHEMBL14037359 | 0.74 | KDM4E (0.36) | MAPK1SMN1; SMN2TUBB1KMT2AMEP1B | |
| SCHEMBL8309433 | 0.70 | — | — | |
| SCHEMBL20560244 | 0.70 | CES2 (0.54) | LMNASMN1; SMN2CES2CES1KMT2A | |
| SCHEMBL9539597 | 0.69 | ESR1 (0.44) | SMN1; SMN2CES2CES1GAA | |
| SCHEMBL24918 | 0.69 | CES2 (0.44) | CES2CES1TUBB1KMT2AMEP1B | |
| SCHEMBL8309818 | 0.69 | LMNA (0.39) | LMNAMAPK1SMN1; SMN2CES2CES1 | |
| SCHEMBL9873091 | 0.68 | KDM4E (0.43) | MAPK1SMN1; SMN2TUBB1KMT2AMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066237-B1 | PROCESSES FOR PREPARING INTERMEDIATES | BAYER CROPSCIENCE SA (FR) | 2005-07-20 | — | — | EP | disclosed |
| US-6642418-B1 | 1,3-dione compounds from beta keto esters | AVENTIS CROPSCIENCE SA (FR) | 2003-11-04 | — | — | US | disclosed |
| EP-1066237-A2 | PROCESSES FOR PREPARING INTERMEDIATES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048851-A2 | PROCESSES FOR PREPARING INTERMEDIATES | AVENTIS CROPSCIENCE S.A. (FR) | 1999-09-30 | — | — | WO | disclosed |
| WO-1998051153-A1 | HERBICIDAL METHODS AND DERIVATIVES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-11-19 | — | — | WO | disclosed |