Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310772 | 0.82 | CES2 (0.33) | CES2CES1 | |
| SCHEMBL6445788 | 0.76 | CES2 (0.38) | LMNAMAPK1SMN1; SMN2MEP1BCES2 | |
| SCHEMBL21712866 | 0.75 | LMNA (0.36) | LMNAMAPK1SMN1; SMN2ADORA3HDAC3 | |
| SCHEMBL9303456 | 0.74 | ADORA3 (0.35) | LMNAMAPK1SMN1; SMN2ADORA3MEN1 | |
| SCHEMBL2601626 | 0.74 | MEN1 (0.50) | LMNAMAPK1SMN1; SMN2MEP1BMEN1 | |
| SCHEMBL8310429 | 0.72 | LMNA (0.42) | LMNAMAPK1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL8309821 | 0.72 | MEN1 (0.33) | LMNAMAPK1SMN1; SMN2MEP1BHDAC3 | |
| SCHEMBL6218614 | 0.70 | MAPT (0.33) | LMNAMAPK1SMN1; SMN2MEP1BCES2 | |
| SCHEMBL1262499 | 0.70 | L3MBTL1 (0.45) | LMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2601628 | 0.70 | MAPT (0.42) | LMNAMAPK1SMN1; SMN2MEP1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |