Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437533 | 0.81 | EZH2 (0.40) | USP30F10TAS1R3TAS1R1TACR2 | |
| SCHEMBL6438399 | 0.71 | AVPR1A (0.36) | PHGDH | |
| SCHEMBL5651921 | 0.66 | CHRM4 (0.42) | USP30TACR2TACR1MAPTLRRK2 | |
| SCHEMBL6439903 | 0.63 | MEN1 (0.41) | USP30TACR2TACR1LRRK2 | |
| SCHEMBL10807044 | 0.61 | OPRD1 (0.59) | F10TAS1R3CHRNA7 | |
| Hydrochloric Acid SCHEMBL10807864 | 0.61 | OPRD1 (0.58) | F10TAS1R3CHRNA7 | |
| SCHEMBL6582988 | 0.60 | MEN1 (0.54) | — | |
| SCHEMBL5651068 | 0.60 | PRSS12 (0.47) | USP30LRRK2 | |
| SCHEMBL5789239 | 0.58 | ACLY (0.46) | PHGDH | |
| SCHEMBL738237 | 0.58 | HTR4 (0.53) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042316-B1 | INDOLE DERIVATIVES USEFUL A.O. FOR THE TREATMENT OF OSTEOPOROSIS | NIKEM RESEARCH SRL (IT) | 2005-02-09 | — | — | EP | claimed |