Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602766 | 0.86 | FNTA (0.49) | MEN1KMT2AALDH1A1GAAPOLB | |
| SCHEMBL27516303 | 0.82 | FNTA (0.39) | MEN1KMT2ATP53ALDH1A1GAA | |
| SCHEMBL6791634 | 0.81 | FNTA (0.38) | KMT2AALDH1A1GAAPOLBMAPT | |
| SCHEMBL1754308 | 0.74 | AKR1C3 (0.58) | MEN1KMT2AALDH1A1LTA4HLMNA | |
| Benzene SCHEMBL28318261 | 0.73 | AKR1C3 (0.61) | MEN1KMT2AALDH1A1GAAMAPK14 | |
| SCHEMBL9749020 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1GAAPOLB | |
| SCHEMBL9231407 | 0.72 | BAZ2B (0.41) | TP53ALDH1A1GAAPOLBLMNA | |
| SCHEMBL2631222 | 0.72 | MAPT (0.42) | MEN1KMT2AALDH1A1GAAPOLB | |
| SCHEMBL27873928 | 0.71 | AKR1C3 (0.65) | ALDH1A1GAAMAPK14LTA4HLMNA | |
| SCHEMBL6791631 | 0.70 | FNTA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601678-A2 | FUSED PYRROLE COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20050014754-A1 | Fused pyrrole compounds | SYNTA PHARMACEUTICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| WO-2004082606-A2 | FUSED PYRROLE COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2004-09-30 | — | — | WO | disclosed |
| WO-2004082606-A2 | FUSED PYRROLE COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014754-A1 | Fused pyrrole compounds | PDE4A, PDE4B, IL4 | MEN1 769/4885KMT2A 2890/4885TP53 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.