Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444435 | 0.76 | DDB1 (0.49) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL5030092 | 0.75 | MEN1 (0.45) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL5025458 | 0.72 | MEN1 (0.43) | SCN9ASCN10AKMT2AMEN1PLA2G10 | |
| SCHEMBL29677014 | 0.71 | MAPK1 (0.46) | PLA2G10PLA2G5 | |
| SCHEMBL6282329 | 0.67 | PLA2G10 (0.47) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL3588482 | 0.67 | SCN9A (0.53) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL6283002 | 0.67 | CYP2D6 (0.65) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL6361822 | 0.66 | PLA2G10 (0.41) | SCN9ASCN10AALDH1A1KDM4EKMT2A | |
| SCHEMBL1364804 | 0.66 | TSHR (0.54) | ALDH1A1KDM4EKMT2AMEN1PLA2G10 | |
| SCHEMBL24495626 | 0.65 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |