Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212522 | 0.85 | TSHR (0.67) | TSHRRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL3191601 | 0.85 | TSHR (0.67) | TSHRRAB9AMAPTL3MBTL1CASP3 | |
| Trifluoromethanesulfonic Acid SCHEMBL404697 | 0.84 | TSHR (0.41) | TSHRCA1CA2CA12CA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL7864823 | 0.82 | MAPK1 (0.35) | TSHRRAB9AMAPTCA12CA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL6118365 | 0.82 | GPR3 (0.48) | CA1CA2CA9PTPN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL37032 | 0.80 | GPR3 (0.50) | TSHRCA1CA2CA9PTPN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL31155703 | 0.80 | GPR3 (0.50) | TSHRCA1CA2CA9PTPN1 | |
| SCHEMBL404698 | 0.80 | MAPK1 (0.38) | TSHRRAB9AMAPTL3MBTL1SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL3143626 | 0.80 | KCNH2 (0.46) | POLBKMT2AALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL36492 | 0.80 | KCNH2 (0.46) | POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | KIT, STS, TST | TSHR 1288/4885RAB9A 619/4885MAPT 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.