Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349990 | 0.98 | DNM1 (0.50) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Acetic Acid SCHEMBL23069469 | 0.88 | ALPL (0.46) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Formic Acid SCHEMBL23069466 | 0.88 | DNM1 (0.42) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Maleic Acid SCHEMBL2350663 | 0.87 | TAAR1 (0.47) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Fumaric Acid SCHEMBL2352005 | 0.87 | TAAR1 (0.47) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL13380707 | 0.86 | KDM4E (0.54) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4650870 | 0.86 | KDM4E (0.54) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL13592680 | 0.86 | KDM4E (0.54) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| Propionic Acid SCHEMBL23069471 | 0.85 | DNM1 (0.44) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL5805398 | 0.84 | DNM1 (0.43) | ALDH1A1TDP1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101508651-A | Method for preparing 3-dehydroabietylamine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | claimed |
| CN-101508650-A | Method for preparing 3-rosin amine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | claimed |
| CN-101508650-A | Method for preparing 3-rosin amine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | disclosed |
| CN-101508651-A | Method for preparing 3-dehydroabietylamine-2-hydroxypropyl dimethyl benzyl ammonium chloride | YANCHENG INST TECHNOLOGY (CN) | 2009-08-19 | — | — | CN | disclosed |
| EP-1546455-A1 | CATIONISED POLYSACCHARIDE PRODUCT | Akzo Nobel N.V. (NL) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031478-A1 | CATIONISED POLYSACCHARIDE PRODUCT | AKZO NOBEL N.V. (NL) | 2004-04-15 | — | — | WO | disclosed |
| EP-1309758-A1 | A PROCESS FOR THE PRODUCTION OF PAPER | Akzo Nobel N.V. (NL) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012626-A1 | A PROCESS FOR THE PRODUCTION OF PAPER | AKZO NOBEL N.V. (NL) | 2002-02-14 | — | — | WO | disclosed |
| EP-1080271-A1 | A PROCESS FOR THE PRODUCTION OF PAPER | Akzo Nobel N.V. (NL) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999055964-A1 | A PROCESS FOR THE PRODUCTION OF PAPER | AKZO NOBEL N.V. (NL) | 1999-11-04 | — | — | WO | disclosed |