Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025462 | 0.81 | ITGB3 (0.63) | MAPK1EPHX1HPGDDRD4NPSR1 | |
| SCHEMBL20911011 | 0.70 | EPHX1 (0.84) | EPHX1HPGDDRD4TSHRNPC1 | |
| SCHEMBL6439601 | 0.70 | ITGB3 (0.54) | MAPK1ITGB3ITGAVTSHRNPC1 | |
| SCHEMBL23349229 | 0.69 | EPHX1 (0.73) | EPHX1HPGDDRD4TSHRNPC1 | |
| SCHEMBL6445537 | 0.69 | ITGB3 (0.49) | MAPK1ITGB3ITGAVTSHRL3MBTL1 | |
| SCHEMBL6444182 | 0.68 | ITGB3 (0.56) | MAPK1HPGDITGB3ITGAVNPC1 | |
| SCHEMBL5028143 | 0.67 | EPHX1 (0.69) | EPHX1HPGDDRD4TSHRNPC1 | |
| SCHEMBL5318930 | 0.67 | EPHX1 (0.69) | EPHX1HPGDDRD4TSHRNPC1 | |
| SCHEMBL5028140 | 0.67 | EPHX1 (0.69) | EPHX1HPGDDRD4TSHRNPC1 | |
| SCHEMBL6440168 | 0.67 | ITGB3 (0.67) | MAPK1ITGB3ITGAVL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |