SCHEMBL6442916

SCHEMBL6442916

C=CC(=O)Oc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.47
HPGD P15428 6/20 0.47
HSD17B10 Q99714 5/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 4/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
THRB P10828 2/20 0.41
THRA P10827 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 4/20 0.38
ESR1 P03372 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
TSHR P16473 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124171 0.83 LMNA (0.52) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL29176099 0.81 LIG1 (0.57) KDM4EHPGDHSD17B10LMNACES2
Acrylic Acid SCHEMBL11117630 0.81 HPGD (0.49) HPGDLMNACES2CES1MAPK1
SCHEMBL20473936 0.81 LMNA (0.46) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL1428878 0.80 LMNA (0.49) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL173919 0.80 KDM4E (0.62) KDM4EHPGDHSD17B10LMNACES2
SCHEMBL6445938 0.79 HPGD (0.49) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL752535 0.79 KDM4E (0.73) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL29378503 0.79 KDM4E (0.73) KDM4EHPGDHSD17B10MAPTLMNA
SCHEMBL30682789 0.79 LMNA (0.55) KDM4EHPGDHSD17B10LMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680364-B1 Water dispersible polyamides with ethylenically unsaturated ends ATOFINA (FR) 2004-01-20 US claimed
EP-1187869-B1 WATER DISPERSIBLE POLYAMIDES WITH ETHYLENICALLY UNSATURATED ENDS ATOFINA (FR) 2002-12-04 EP claimed
US-8642716-B2 Branched polyamides comprising unsaturated ends ARKEMA FRANCE (FR) 2014-02-04 US disclosed
US-20050245680-A1 Branched polyamides comprising unsaturated ends ARKEMA FRANCE (FR) 2005-11-03 US disclosed