Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428878 | 0.87 | LMNA (0.49) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL173919 | 0.87 | KDM4E (0.62) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL30682789 | 0.86 | LMNA (0.55) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL20473936 | 0.84 | LMNA (0.46) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL6445938 | 0.83 | HPGD (0.49) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL6442916 | 0.83 | KDM4E (0.47) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL277654 | 0.83 | HPGD (0.56) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL29210396 | 0.82 | HPGD (0.43) | KDM4EHPGDHSD17B10ALDH1A1TDP1 | |
| SCHEMBL459657 | 0.81 | CTNNB1 (0.57) | LMNACES2CES1MAPK1KDM4E | |
| Methoxymethane SCHEMBL5593577 | 0.81 | HPGD (0.55) | LMNACES2CES1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815114-B1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 2004-05-12 | — | — | EP | claimed |
| US-5908926-A | 5'to 3' nucleic acid synthesis using 3'-photoremovable protecting group | DUKE UNIVERSITY (US) | 1999-06-01 | — | — | US | claimed |
| EP-0815114-A4 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 1999-02-24 | — | — | EP | claimed |
| EP-0815114-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1998-01-07 | — | — | EP | claimed |
| WO-1996028457-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1996-09-19 | — | — | WO | claimed |
| EP-2159290-B1 | Method of producing microarray having immobilized double-stranded nucleic acid probe including double-stranded region and single-stranded region | SAMSUNG ELECTRONICS CO LTD (KR) | 2012-03-07 | — | — | EP | disclosed |
| US-20100056397-A1 | Method of Producing Microarray Having Immobilized Double-Stranded Nucleic Acid Probe Including Double-Stranded Region and Single-Stranded Region | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-03-04 | — | — | US | disclosed |
| EP-2159290-A1 | Method of producing microarray having immobilized double-stranded nucleic acid probe including double-stranded region and single-stranded region | Samsung Electronics Co., Ltd. (KR) | 2010-03-03 | — | — | EP | disclosed |
| CN-101660211-A | Method of producing microarray having immobilized double-stranded nucleic acid probe | SAMSUNG ELECTRONICS CO LTD | 2010-03-03 | — | — | CN | disclosed |
| EP-0815114-B1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 2004-05-12 | — | — | EP | disclosed |
| US-5908926-A | 5'to 3' nucleic acid synthesis using 3'-photoremovable protecting group | DUKE UNIVERSITY (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0815114-A4 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0815114-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996028457-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1996-09-19 | — | — | WO | disclosed |