SCHEMBL173919

SCHEMBL173919

CC(=O)Oc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.62
HSD17B10 Q99714 4/20 0.62
HPGD P15428 4/20 0.62
PTGS2 P35354 3/20 0.62
ALDH1A1 P00352 3/20 0.62
ESR1 P03372 1/20 0.62
ITGB3 P05106 1/20 0.62
ITGA2B P08514 1/20 0.62
HMGB1 P09429 1/20 0.62
TSHR P16473 1/20 0.62
GGT1 P19440 1/20 0.62
PTGS1 P23219 1/20 0.62
BLM P54132 1/20 0.62
NAPRT Q6XQN6 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
LMNA P02545 4/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
MAPK1 P28482 2/20 0.49
CES2 O00748 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124171 0.87 LMNA (0.52) KDM4EHSD17B10HPGDPTGS2ALDH1A1
SCHEMBL6445938 0.86 HPGD (0.49) KDM4EHSD17B10HPGDPTGS2ALDH1A1
SCHEMBL1428878 0.84 LMNA (0.49) KDM4EHSD17B10HPGDPTGS2ALDH1A1
SCHEMBL277654 0.83 HPGD (0.56) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL30682789 0.83 LMNA (0.55) KDM4EHSD17B10HPGDPTGS2ALDH1A1
Methoxymethane SCHEMBL5593577 0.82 HPGD (0.55) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL20473936 0.81 LMNA (0.46) KDM4EHSD17B10HPGDPTGS2ALDH1A1
SCHEMBL2818437 0.81 IRAK4 (0.58) KDM4EHSD17B10HPGDALDH1A1TDP1
SCHEMBL6442916 0.80 KDM4E (0.47) KDM4EHSD17B10HPGDPTGS2ALDH1A1
SCHEMBL9463272 0.80 KDM4E (0.66) KDM4EHSD17B10HPGDPTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108676063-A A kind of double acyloxy bisamide class pharmaceutical intermediates of hydroxyl and preparation method thereof 三峡大学 2018-10-19 CN claimed
CN-106363235-B A kind of construction field ground material automatic double synchronous cutting equipment and its working method based on PLC controls 徐州工程学院 2018-08-14 CN claimed
CN-107722014-A Salt as hepatitis C virus inhibitors 广东东阳光药业有限公司 2018-02-23 CN claimed
CN-103228609-B Method for producing acyloxybenzoic acids WEIR CHEMICAL SWITZERLAND LTD 2015-01-07 CN claimed
US-5039717-A Injection molding cookwear AMOCO CORPORATION (US) 1991-08-13 US claimed
WO-2025072686-A1 KRAS G12D MUTATION TARGETING COMPOUNDS SUMMIT THERAPEUTICS INC. (US) 2025-04-03 WO disclosed
WO-2025059556-A1 COMPOSITIONS COMPRISING PRALATREXATE FOR SUBCUTANEOUS ADMINISTRATION AND METHODS OF USE THEREOF Acrotech Biopharma Inc. (US) 2025-03-20 WO disclosed
EP-4333903-A1 COMPOSITIONS AND METHODS RELATED TO THE TREATMENT OF OCULAR DISEASES IN EQUINES North Carolina State University (US) 2024-03-13 EP disclosed
CN-117500494-A Advantageous anti-HCV combination therapies 阿堤亚制药公司 2024-02-02 CN disclosed
WO-2023281272-A1 NASAL SPRAY Pollinner Limited (GB) 2023-01-12 WO disclosed
WO-2023278827-A1 3-IODOPROPYL-1,2,3-TRIAZOL-1-YL, 3-BROMOPROPYL-1,2,3-TRIAZOL-1-YL, AND DERIVATIVES FOR USES IN LABELING EMORY UNIVERSITY (US) 2023-01-05 WO disclosed
WO-2022235566-A1 COMPOSITIONS AND METHODS RELATED TO THE TREATMENT OF OCULAR DISEASES IN EQUINES NORTH CAROLINA STATE UNIVERSITY (US) 2022-11-10 WO disclosed
EP-0329904-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329905-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for increasing gastric motility MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329903-A1 Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of glaucoma MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329932-A2 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments MERRELL PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0284256-A1 Benzodiazepine analogs MERCK & CO. INC. (US) 1988-09-28 EP disclosed
EP-0099080-B1 SUBSTITUTED TETRAHYDROTETRAZOLO(5,1-A)PHTHALAZINES THE DOW CHEMICAL COMPANY (US) 1988-02-03 EP disclosed
CN-85109752-A Preparation triterpenoid organic acid ester and the method that contains the hypolipidemic agents of this compounds 1986-12-17 CN disclosed
US-4021565-A Process for the alleviation of depression by administration of non-addicting meperidine analogues BERGER FRANK M 1977-05-03 US disclosed