SCHEMBL6445938

SCHEMBL6445938

C=C(C)C(=O)Oc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.49
KDM4E B2RXH2 7/20 0.45
HSD17B10 Q99714 5/20 0.45
ALDH1A1 P00352 5/20 0.45
ESR1 P03372 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
HMGB1 P09429 1/20 0.45
TSHR P16473 1/20 0.45
GGT1 P19440 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
BLM P54132 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
LMNA P02545 4/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ELANE P08246 3/20 0.43
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173919 0.86 KDM4E (0.62) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL20473936 0.84 LMNA (0.46) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL124171 0.83 LMNA (0.52) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL1428878 0.80 LMNA (0.49) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL277654 0.80 HPGD (0.56) HPGDKDM4EHSD17B10ALDH1A1LMNA
SCHEMBL6442916 0.79 KDM4E (0.47) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL344654 0.79 KDM4E (0.70) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL29981543 0.79 KDM4E (0.70) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL30682789 0.79 LMNA (0.55) HPGDKDM4EHSD17B10ALDH1A1ESR1
SCHEMBL16966572 0.79 KDM4E (0.70) HPGDKDM4EHSD17B10ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187869-B1 WATER DISPERSIBLE POLYAMIDES WITH ETHYLENICALLY UNSATURATED ENDS ATOFINA (FR) 2002-12-04 EP claimed
EP-0296220-A4 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS. CHANG SING-HSIUNG (US) 1989-05-11 EP claimed
EP-0296220-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG, Sing-Hsiung (US) 1988-12-28 EP claimed
WO-1988005060-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG SING HSIUNG (US) 1988-07-14 WO claimed
US-8642716-B2 Branched polyamides comprising unsaturated ends ARKEMA FRANCE (FR) 2014-02-04 US disclosed
US-20050245680-A1 Branched polyamides comprising unsaturated ends ARKEMA FRANCE (FR) 2005-11-03 US disclosed
US-6680364-B1 Water dispersible polyamides with ethylenically unsaturated ends ATOFINA (FR) 2004-01-20 US disclosed
US-4985198-A (METH)ACRYLOYLOXYBENZOIC ACID POLYMERS G-C DENTAL INDUSTRIAL CORP. (JP) 1991-01-15 US disclosed
US-4112212-A Ultra-high molecular weight polymethacryloyloxybenzoic acid and method of preparation CELANESE CORPORATION (US) 1978-09-05 US disclosed