Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.49 |
| ▸ | CTSB | P07858 | 9/20 | 0.49 |
| ▸ | CTSS | P25774 | 7/20 | 0.49 |
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSV | O60911 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446816 | 0.90 | GAA (0.40) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6443960 | 0.86 | CTSB (0.44) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6447899 | 0.84 | CTSL (0.54) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6444325 | 0.83 | CTSL (0.48) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6447506 | 0.83 | CTSL (0.53) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6824499 | 0.81 | CTSL (0.62) | CTSL | |
| SCHEMBL6019797 | 0.81 | CTSL (0.62) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6822562 | 0.81 | CTSK (0.47) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6447466 | 0.78 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6020316 | 0.77 | CTSL (0.78) | CTSLCTSBCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |