Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | RAB9A | P51151 | 2/20 | 0.85 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374341 | 0.92 | MAPT (1.00) | MAPTLMNARAB9ATLR9MEN1 | |
| 2-Nitrofluorene SCHEMBL644332 | 0.91 | MAPT (0.68) | MAPTLMNARAB9ATLR9MEN1 | |
| 2-Nitrofluorene SCHEMBL29450702 | 0.91 | MAPT (0.68) | MAPTLMNARAB9ATLR9MEN1 | |
| 2-Nitrofluorene SCHEMBL28186600 | 0.86 | MAPT (0.62) | MAPTLMNARAB9ATLR9MEN1 | |
| 2-Nitrofluorene SCHEMBL28251179 | 0.85 | MAPT (0.60) | MAPTLMNARAB9ATLR9MEN1 | |
| SCHEMBL14182815 | 0.85 | RAB9A (0.85) | MAPTLMNARAB9ATLR9MEN1 | |
| SCHEMBL7618863 | 0.84 | MAPT (0.58) | MAPTLMNARAB9ATLR9MEN1 | |
| SCHEMBL12298162 | 0.83 | PTPRC (0.58) | MAPTLMNARAB9ATLR9MEN1 | |
| SCHEMBL7275458 | 0.83 | MEN1 (0.81) | MAPTLMNARAB9ATLR9MEN1 | |
| SCHEMBL23989284 | 0.82 | RAB9A (1.00) | MAPTLMNARAB9ATLR9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015811-A | Antitumor Chrysene derivatives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-01-18 | — | — | US | disclosed |