Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123279 | 0.89 | TSHR (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL28775846 | 0.86 | CES2 (0.59) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL247590 | 0.86 | CES2 (0.59) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL8923096 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL8798021 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL11762738 | 0.82 | MAOB (0.73) | ALDH1A1KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL4493359 | 0.82 | MAPT (0.54) | ALDH1A1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL18050295 | 0.80 | CES2 (0.52) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL18050293 | 0.80 | CES2 (0.52) | ALDH1A1CES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL8030701 | 0.80 | CA12 (0.61) | ALDH1A1KMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | claimed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | claimed |
| US-20050153404-A1 | Anti-kazlauskas lipases | LANXESS DEUTSCHLAND GMBH (DE) | 2005-07-14 | — | — | US | claimed |
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-108929226-B | Method for preparing benzoyl formate derivative | 广东工业大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-111393291-A | Novel synthesis method of α -carbonyl acid ester | 宁波海曙琼杰化工技术研发工作室 | 2020-07-10 | — | — | CN | disclosed |
| EP-1215216-B1 | Cellulose ester of aromatic carboxylic acid | FUJI PHOTO FILM CO LTD (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-20050153404-A1 | Anti-kazlauskas lipases | LANXESS DEUTSCHLAND GMBH (DE) | 2005-07-14 | — | — | US | disclosed |
| EP-1215216-A1 | Cellulose ester of aromatic carboxylic acid | FUJI PHOTO FILM CO., LTD. (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| US-3932182-A | An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153404-A1 | Anti-kazlauskas lipases | CEL, LIPA, LPL | ALDH1A1 735/4885CES2 22/4885CES1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.