Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273175 | 0.88 | RAB9A (0.44) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5270032 | 0.79 | POLB (0.54) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5272037 | 0.79 | POLB (0.54) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5268041 | 0.78 | SMN1; SMN2 (0.49) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5268227 | 0.77 | TP53 (0.41) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5274435 | 0.77 | RAPGEF4 (0.42) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL13267555 | 0.76 | LMNA (0.53) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL13627131 | 0.76 | LMNA (0.53) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5269101 | 0.75 | CASR (0.46) | LMNATP53HTTRAB9AMEN1 | |
| SCHEMBL5269254 | 0.75 | ADRB2 (0.42) | LMNAHTTMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894190-B2 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-17 | — | — | US | disclosed |