SCHEMBL6445041

SCHEMBL6445041

CC1=C([Si](C)(C)C)c2ccccc2C1(Cl)[SiH2]C1(Cl)C(C)=C([Si](C)(C)C)c2ccccc21.[Zr]

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3354011 0.75 S100A4 (0.33) S100A4
SCHEMBL4275883 0.75 S100A4 (0.33) S100A4
SCHEMBL4054488 0.73 MAPT (0.34) S100A4
SCHEMBL7645540 0.73 CYP2D6 (0.33) S100A4
SCHEMBL7646786 0.70 CYP2D6 (0.33) S100A4
SCHEMBL4315247 0.70 MAPT (0.34) S100A4
SCHEMBL7643159 0.70 CYP2D6 (0.33) S100A4
SCHEMBL4063433 0.69 MITF (0.31)
SCHEMBL7007867 0.68
SCHEMBL6464431 0.67 PDCD1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6841634-B1 Modified supported catalysts for the polymerization of olefins BOREALIS TECHNOLOGY OY (FI) 2005-01-11 US disclosed
US-5932514-A HEATING MIXTURE OF METAL OXIDES AND ORGANOALUMINUM COMPOUND BOREALIS AG (AT) 1999-08-03 US disclosed