SCHEMBL4054488

SCHEMBL4054488

CC1=C(c2ccccc2)c2ccccc2C1(Cl)[SiH2]C1(Cl)C(C)=C(c2ccccc2)c2ccccc21.[Zr]

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
MITF O75030 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSP90AA1 P07900 2/20 0.33
HSP90AB1 P08238 2/20 0.33
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2A6 P11509 1/20 0.31
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
S100A4 P26447 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646165 0.97 MAPT (0.34) MAPTMITFALDH1A1HTTNPSR1
SCHEMBL4315247 0.97 MAPT (0.34) MAPTMITFALDH1A1HTTNPSR1
SCHEMBL4063433 0.94 MITF (0.31) MAPTMITFALDH1A1HTTNPSR1
SCHEMBL4061870 0.80 SLC6A2 (0.32)
SCHEMBL7929749 0.77 PDCD1 (0.32) MAPTMITFALDH1A1HTTNPSR1
SCHEMBL6464431 0.76 PDCD1 (0.33) CYP2A6
SCHEMBL1531948 0.76 PDCD1 (0.33) CYP2A6
SCHEMBL5178882 0.76 FABP4 (0.33)
SCHEMBL3354011 0.75 S100A4 (0.33) S100A4
SCHEMBL4275883 0.75 S100A4 (0.33) S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045304-A2 Polypropylene-Based Adhesive Compositions ExxonMobil Chemical Patents Inc. (US) 2009-04-08 EP disclosed
EP-1311593-B1 POLYPROPYLENE FILMS EXXONMOBIL CHEM PATENTS INC (US) 2009-01-07 EP disclosed
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US disclosed
EP-1315858-B1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEM PATENTS INC (US) 2007-02-07 EP disclosed
EP-1237957-B1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2006-08-23 EP disclosed
US-20040254316-A1 Polymerization processes using antistatic agents EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-16 US disclosed
US-20040171782-A1 Polypropylene polymers EXXONMOBIL CHEMICAL PATENTS INC. 2004-09-02 US disclosed
US-20040110886-A1 Polypropylene-based adhesive compositions KARANDINOS ANTHONY GEORGE (BE) 2004-06-10 US disclosed
US-20040030050-A1 Polypropylene films EXXONMOBIL CHEMICAL PATENTS INC. 2004-02-12 US disclosed
US-6667272-B2 Metallocene, an activator and a fluorided support; use as alpha-olefin polymerization catalysts, polypropylene EXXONMOBIL CHEMICAL PATENTS INC. 2003-12-23 US disclosed
WO-2002016681-A1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
US-20020019507-A1 Polypropylene-based adhesive compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-02-14 US disclosed
US-20010049331-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-06 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed
US-20010039314-A1 Propylene polymers for films EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-08 US disclosed
WO-2001036497-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001036499-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001032757-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-05-10 WO disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed