Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 8/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 5/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445490 | 0.92 | ANPEP (0.51) | ANPEPKMT2ACTSSCTSKMEN1 | |
| SCHEMBL6019506 | 0.88 | CTSS (0.53) | ANPEPCTSSCTSKCTSLCTSB | |
| SCHEMBL6446628 | 0.85 | KMT2A (0.70) | ANPEPKMT2ACTSSCTSKCTSL | |
| SCHEMBL6446714 | 0.84 | ANPEP (0.57) | ANPEPKMT2ACTSSCTSKMEN1 | |
| SCHEMBL6020101 | 0.82 | ANPEP (0.48) | ANPEPCTSSCTSKCTSLCTSB | |
| SCHEMBL6822714 | 0.81 | CTSL (0.68) | KMT2ACTSSCTSKCTSLCTSB | |
| SCHEMBL6020136 | 0.80 | CTSB (0.55) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6020089 | 0.80 | CTSS (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6020085 | 0.80 | CTSS (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6019564 | 0.79 | CTSL (0.76) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |