Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.56 |
| ▸ | ABAT | P80404 | 2/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203126 | 0.85 | APP (0.63) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL856737 | 0.85 | APP (0.63) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL6442449 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL8466367 | 0.78 | ALDH1A1 (0.66) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL12189867 | 0.77 | ALDH1A1 (0.69) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL21807873 | 0.76 | ALOX15 (0.45) | HPGDAPP | |
| SCHEMBL9989357 | 0.75 | ALDH1A1 (0.71) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL6445432 | 0.75 | HSD17B10 (0.41) | ALDH1A1HPGDTDP1APPTSHR | |
| Vanillin SCHEMBL29354839 | 0.72 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| Vanillin SCHEMBL1213 | 0.72 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATTRIM24HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893444-B1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-5936102-A | CYCLOCONDENSING O-(2-BROMOTETRAFLUOROETHOXY)PHENOL IN THE PRESENCE OF ACID BINDER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |
| EP-0893444-A1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | BAYER AG (DE) | 1999-01-27 | — | — | EP | disclosed |