Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.66 |
| ▸ | ABAT | P80404 | 2/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869201 | 0.86 | ALDH1A1 (0.66) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL29991604 | 0.83 | ALDH1A1 (0.57) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL18883604 | 0.83 | ALDH1A1 (0.57) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL856737 | 0.82 | APP (0.63) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL30203126 | 0.82 | APP (0.63) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL686127 | 0.82 | TRPA1 (0.66) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| Vanillin SCHEMBL1213 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| Vanillin SCHEMBL29354839 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| Vanillin SCHEMBL720723 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALDH5A1ABATTRIM24HPGD | |
| SCHEMBL16972475 | 0.79 | APP (0.70) | ALDH1A1HPGDTDP1KDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709361-B1 | Process for the preparation of isovanilline | RHODIA CHIMIE SA (FR) | 1999-02-03 | — | — | EP | claimed |
| US-5786516-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1998-07-28 | — | — | US | claimed |
| US-5648552-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1997-07-15 | — | — | US | claimed |
| EP-0709361-A1 | Process for the preparation of isovanilline | RHONE-POULENC CHIMIE (FR) | 1996-05-01 | — | — | EP | claimed |
| US-12466795-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2025-11-11 | — | — | US | disclosed |
| US-20240150288-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2024-05-09 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| EP-4023294-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Cognition Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-4023294-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Cognition Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3498692-B1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE AND MACULAR DEGENERATION | COGNITION THERAPEUTICS INC (US) | 2022-03-16 | — | — | EP | disclosed |
| WO-2015116923-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015116923-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2015-08-06 | — | — | WO | disclosed |
| CN-100361994-C | Tetraphenyl porphyrin derivative and its application in organic electroluminescent device | UNIV JILIN (CN) | 2008-01-16 | — | — | CN | disclosed |
| CN-1631890-A | Tetraphenyl porphyrin derivative and its application in organic electroluminescent device | UNIV JILIN (CN) | 2005-06-29 | — | — | CN | disclosed |
| EP-0709361-B1 | Process for the preparation of isovanilline | RHODIA CHIMIE SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| US-5786516-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1998-07-28 | — | — | US | disclosed |
| US-5648552-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1997-07-15 | — | — | US | disclosed |
| EP-0709361-A1 | Process for the preparation of isovanilline | RHONE-POULENC CHIMIE (FR) | 1996-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH5A1 3758/4885ABAT 1729/4885 |
| US-20240150288-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH5A1 3758/4885ABAT 1729/4885 |
| US-12466795-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH5A1 3758/4885ABAT 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.