Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28564703 | 0.84 | AKR1C3 (0.66) | ALDH1A1PLK1LTC4SKDM4ECDC25A | |
| SCHEMBL5314074 | 0.84 | AKR1C3 (0.66) | ALDH1A1PLK1LTC4SKDM4ECDC25A | |
| SCHEMBL28687869 | 0.82 | AKR1C3 (0.64) | ALDH1A1PLK1LTC4SKDM4ECDC25A | |
| SCHEMBL27476186 | 0.81 | KDM4E (0.62) | ALDH1A1LTC4SKDM4ETDP1CDC25A | |
| SCHEMBL5310985 | 0.81 | AKR1C3 (0.56) | ALDH1A1LTC4SKDM4ECDC25ACDC25B | |
| SCHEMBL6056943 | 0.80 | RARB (0.63) | ALDH1A1PLK1MAPTMEN1KMT2A | |
| SCHEMBL6056939 | 0.80 | RARB (0.63) | ALDH1A1PLK1MAPTMEN1KMT2A | |
| SCHEMBL6056900 | 0.80 | RARB (0.63) | ALDH1A1PLK1MAPTMEN1KMT2A | |
| SCHEMBL7822787 | 0.80 | CYP2C8 (0.64) | ALDH1A1KDM4ESRD5A2TDP1CDC25A | |
| SCHEMBL2935942 | 0.80 | ALDH1A1 (0.70) | ALDH1A1PLK1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288522-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-29 | — | — | US | disclosed |
| US-6974877-B2 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| EP-1430008-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M Innovative Properties Company (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030100779-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| US-20030097010-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-22 | — | — | US | disclosed |
| WO-2003027050-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288522-A1 | Process for preparing pentacene derivatives | RARA, RARB, C9 | ALDH1A1 1561/4885PLK1 2637/4885LTC4S 2779/4885 |
| US-20030097010-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | ALDH1A1 1091/4885PLK1 3027/4885LTC4S 3088/4885 |
| US-20030100779-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | ALDH1A1 1091/4885PLK1 3027/4885LTC4S 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.