Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365525 | 0.85 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL6450390 | 0.71 | MEN1 (0.33) | CYP3A4 | |
| SCHEMBL6451074 | 0.69 | PTGS1 (0.32) | — | |
| SCHEMBL2691332 | 0.66 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL6446484 | 0.65 | ALK (0.34) | CYP3A4 | |
| SCHEMBL1726478 | 0.65 | NCOA1 (0.43) | — | |
| SCHEMBL6439097 | 0.65 | MITF (0.42) | — | |
| SCHEMBL6450955 | 0.65 | KDM4E (0.34) | — | |
| SCHEMBL10090578 | 0.64 | NPC1 (0.35) | CYP3A4 | |
| SCHEMBL1543258 | 0.63 | ALDH1A1 (0.38) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168792-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20100226879-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | ABBOT SARAH C | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226879-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | POLR2A, IFNAR1, RRM2B | GSK3B 1644/4885CYP3A4 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.