Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170324 | 0.86 | MAPK1 (0.51) | KDM4EMAPK1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL1646977 | 0.82 | POLB (0.45) | KDM4ETSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL28919121 | 0.82 | KMT2A (0.55) | KDM4ETSHRBACE1MAPK1USP2 | |
| SCHEMBL31403415 | 0.79 | CYP4F2 (0.47) | KDM4ETSHRBACE1MAPK1CYP3A4 | |
| SCHEMBL23389812 | 0.76 | KMT2A (0.55) | KDM4ETSHRMAPK1CYP3A4KMT2A | |
| SCHEMBL7195213 | 0.76 | POLB (0.55) | KDM4EMAPK1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL8481431 | 0.75 | ALDH1A1 (0.56) | KDM4ETSHRMAPK1CYP3A4KMT2A | |
| SCHEMBL2382494 | 0.75 | CYP3A4 (0.53) | KDM4EMAPK1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL21995828 | 0.75 | TAAR1 (0.42) | KDM4ETSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL28453775 | 0.75 | GPR35 (0.41) | KDM4ETSHRMAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238961-B1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | BAYER CHEMICALS AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6600064-B2 | Reacting dibenzyl ethers with alkylcarbonyloxybenzoic or alkoxycarbonyloxybenzoic acids in the presence of one or more acids as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-1238961-A1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | Bayer Aktiengesellschaft (DE) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, ALKBH3 | KDM4E 202/4885TSHR 4424/4885BACE1 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.