Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CPS1 | P31327 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170324 | 0.88 | MAPK1 (0.51) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL23389812 | 0.88 | KMT2A (0.55) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL7195213 | 0.88 | POLB (0.55) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL21995828 | 0.87 | TAAR1 (0.42) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL28453775 | 0.87 | GPR35 (0.41) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL30039499 | 0.84 | GPR35 (0.42) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL2382494 | 0.83 | CYP3A4 (0.53) | POLBMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL6445568 | 0.82 | KDM4E (0.45) | POLBMAPK1KMT2AKDM4EGAA | |
| SCHEMBL9241705 | 0.81 | TAAR1 (0.52) | POLBMAPK1HTTRAB9ATAAR1 | |
| SCHEMBL1759022 | 0.81 | TAAR1 (0.42) | MAPK1MAPTHTTRAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577206-B2 | Pyrazolone formyl peptide 2 receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4541422-A2 | QUINOLINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS | Gilead Sciences, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| EP-4523755-A2 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | F. Hoffmann-La Roche AG (CH) | 2025-03-19 | — | — | EP | disclosed |
| CN-119462635-A | Quinoline derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20250032473-A1 | QUINOLINE DERIVATIVES | GILEAD SCIENCES, INC. | 2025-01-30 | — | — | US | disclosed |
| EP-3873884-B1 | 3-(QUINOLIN-8-YL)-1,4-DIHYDROPYRIDO[3,4-D]PYRIMIDIN-2,4-DIONE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | GILEAD SCIENCES INC (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4360713-B1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2024-10-30 | — | — | EP | disclosed |
| EP-4178949-B9 | PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-112969687-B | Quinoline derivatives as a4 b 7 integrin inhibitors | 吉利德科学公司 | 2024-08-23 | — | — | CN | disclosed |
| US-12053462-B2 | Quinoline derivatives | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0407438-B1 | LATERALLY FLUORINATED 4-CYANOPHENYL AND 4'-CYANOBIPHENYL BENZOATES | SECR DEFENCE BRIT (GB) | 1995-01-04 | — | — | EP | disclosed |
| US-5334327-A | Nematic liquid crystal display device | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTH IRELAND (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5156763-A | Liquid crystals | THE SECRETARY OF STATE FOR FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-10-20 | — | — | US | disclosed |
| EP-0407438-A1 | LATERALLY FLUORINATED 4-CYANOPHENYL AND 4'-CYANOBIPHENYL BENZOATES. | SECR DEFENCE BRIT (GB) | 1991-01-16 | — | — | EP | disclosed |
| WO-1989008102-A1 | LATERALLY FLUORINATED 4-CYANOPHENYL AND 4'-CYANOBIPHENYL BENZOATES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1989-09-08 | — | — | WO | disclosed |
| EP-0031199-B1 | SUBSTITUTED BENZYL ESTERS OF CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND METHODS OF COMBATING INSECT PESTS THEREWITH, AND SUBSTITUTED BENZYL ALCOHOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-14 | — | — | EP | disclosed |
| EP-0060617-A1 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0031199-A1 | Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053462-B2 | Quinoline derivatives | CFTR, NQO1, IRF3 | POLB 2716/4885MAPK1 521/4885KMT2A 2755/4885 |
| US-12577206-B2 | Pyrazolone formyl peptide 2 receptor agonists | FPR2, FPR1, FPR3 | POLB 3745/4885MAPK1 927/4885KMT2A 4664/4885 |
| US-20250032473-A1 | QUINOLINE DERIVATIVES | CFTR, NQO1, IRF3 | POLB 2716/4885MAPK1 521/4885KMT2A 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.