Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ERN1 | O75460 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310021 | 0.86 | ERN1 (0.58) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL31084750 | 0.86 | ERN1 (0.58) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL16533324 | 0.85 | MAPT (0.61) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL21660344 | 0.85 | ALDH1A1 (0.59) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL2961633 | 0.84 | CA12 (0.65) | ERN1ALDH1A1LMNACA1CA2 | |
| SCHEMBL23459305 | 0.84 | MAPT (0.49) | MAPTERN1KMT2AALDH1A1LMNA | |
| SCHEMBL8992939 | 0.84 | HSD17B2 (0.66) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL17747083 | 0.84 | ALDH1A1 (0.58) | MAPTERN1KMT2AALDH1A1MEN1 | |
| SCHEMBL25242944 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CA1CA2 | |
| SCHEMBL8112678 | 0.83 | MAPT (0.55) | MAPTERN1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368667-A1 | USP1 INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RES AND DEVELOPMENT CENTRE LTD (CN) | 2025-12-04 | — | — | US | disclosed |
| EP-4582427-A1 | USP1 INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2025-07-09 | — | — | EP | disclosed |
| US-12258316-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2025-03-25 | — | — | US | disclosed |
| CN-119497713-A | USP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-118184658-A | USP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024046471-A9 | USP1 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-05-02 | — | — | WO | disclosed |
| CN-117776883-A | Preparation method of aromatic ketone compound containing diaryl methane structure | 湖南科技大学 | 2024-03-29 | — | — | CN | disclosed |
| WO-2024046471-A1 | USP1 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-03-07 | — | — | WO | disclosed |
| CN-114181061-B | Preparation method of aromatic ketone compound containing diaryl methane structure | 湖南科技大学 | 2024-01-23 | — | — | CN | disclosed |
| US-20220306579-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2022-09-29 | — | — | US | disclosed |
| WO-2000026197-A1 | NOVEL INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0831891-A4 | OXIDANT SCAVENGERS | UNIV DUKE (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0831891-A1 | OXIDANT SCAVENGERS | DUKE UNIVERSITY (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997005114-A1 | QUINOLONE SULFONIMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |
| WO-1996040223-A1 | OXIDANT SCAVENGERS | DUKE UNIVERSITY (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4753962-A | HYPOGLYCEMIC, ANTIOBESITY AGENT | BEECHAM GROUP P.L.C. (GB) | 1988-06-28 | — | — | US | disclosed |
| US-4654371-A | ANTI-OBESITY, HYPOGLYCEMIA AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-31 | — | — | US | disclosed |
| US-4478849-A | HYPERGLYCEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1984-10-23 | — | — | US | disclosed |
| EP-0006735-B1 | SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306579-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM1, CHRM3 | MAPT 4020/4885ERN1 3280/4885KMT2A 2049/4885 |
| US-20250368667-A1 | USP1 INHIBITOR | USP1, USP2, USP28 | MAPT 2468/4885ERN1 289/4885KMT2A 2034/4885 |
| US-12258316-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | CHRM2, CHRM1, CHRM3 | MAPT 4020/4885ERN1 3280/4885KMT2A 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.