Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952899 | 0.81 | TSHR (0.58) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL6444922 | 0.81 | CES2 (0.65) | TSHRERCC5FEN1CES2CES1 | |
| SCHEMBL7032023 | 0.81 | TSHR (0.71) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL9693738 | 0.80 | KAT6A (0.47) | TSHRP2RX7CES2CES1ALDH1A1 | |
| SCHEMBL97298 | 0.79 | TSHR (1.00) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL2831621 | 0.79 | TSHR (0.68) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL29904615 | 0.79 | TSHR (1.00) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL93365 | 0.79 | TSHR (0.68) | TSHRERCC5FEN1P2RX7CES2 | |
| Fluoride SCHEMBL6446007 | 0.77 | TSHR (0.95) | TSHRERCC5FEN1P2RX7CES2 | |
| SCHEMBL2048711 | 0.77 | TSHR (0.95) | TSHRERCC5FEN1P2RX7CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233010-B1 | Method for production of organic fluorine compound | NIPPON CATALYTIC CHEM IND (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0899256-B1 | Method for production of organic fluorine compound | NIPPON CATALYTIC CHEM IND (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1233010-A1 | Method for production of organic fluorine compound | Nippon Shokubai Co., Ltd. (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-6392084-B1 | FLUORINATION OF AN ORGANO(BROMINE OR CHLORIDE) COMPOUND IN BENZONITRILE SOLVENT | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0899256-A2 | Method for production of organic fluorine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0885249-A2 | FLUORINATION PROCESS USING HYDROGEN FLUORIDE-CONTAINING FLUORINATING AGENTS | AlliedSignal Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885166-A1 | PROCESS FOR HYDROGEN FLUORIDE SEPARATION | AlliedSignal Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5705717-A | Fluorination process using hydrogen fluoride-containing fluorinating agents | ALLIEDSIGNAL INC. (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997032809-A1 | PROCESS FOR HYDROGEN FLUORIDE SEPARATION | ALLIEDSIGNAL INC. (US) | 1997-09-12 | — | — | WO | disclosed |
| WO-1997032907-A2 | FLUORINATION PROCESS USING HYDROGEN FLUORIDE-CONTAINING FLUORINATING AGENTS | ALLIEDSIGNAL INC. (US) | 1997-09-12 | — | — | WO | disclosed |
| US-5632966-A | Process for hydrogen fluoride separation | ALLIEDSIGNAL INC. (US) | 1997-05-27 | — | — | US | disclosed |