SCHEMBL6446131

SCHEMBL6446131

CCN(C#N)C(=O)N(CCS(C)(=O)=O)C(=O)/C=C/C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6446134 1.00 ZDHHC20 (0.40) ZDHHC20
SCHEMBL6442098 0.83 ZDHHC20 (0.39) ZDHHC20
SCHEMBL6442100 0.83 ZDHHC20 (0.39) ZDHHC20
SCHEMBL6445379 0.75 ALDH1A1 (0.39) ZDHHC20
SCHEMBL6445383 0.75 ALDH1A1 (0.39) ZDHHC20
SCHEMBL6446747 0.74 ATG4B (0.35) ZDHHC20
SCHEMBL6446750 0.74 ATG4B (0.35) ZDHHC20
SCHEMBL6442445 0.69 PDPK1 (0.40)
SCHEMBL6446217 0.62 ZDHHC20 (0.37) ZDHHC20
SCHEMBL6446222 0.62 ZDHHC20 (0.37) ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004056755-A2 COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES JERENI AG (DE) 2004-07-08 WO claimed
EP-1575903-A1 COMPOUNDS FOR THE INHIBITION OF ROTAMASES Jerini AG (DE) 2005-09-21 EP disclosed
WO-2004065353-A1 COMPOUNDS FOR THE INHIBITION OF ROTAMASES JERINI AG (DE) 2004-08-05 WO disclosed
WO-2004056755-A2 COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES JERENI AG (DE) 2004-07-08 WO disclosed