Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446222 | 1.00 | ZDHHC20 (0.37) | ZDHHC20MEN1KMT2A | |
| SCHEMBL6447479 | 0.83 | ZDHHC20 (0.38) | ZDHHC20 | |
| SCHEMBL6447478 | 0.83 | ZDHHC20 (0.38) | ZDHHC20 | |
| SCHEMBL6442100 | 0.78 | ZDHHC20 (0.39) | ZDHHC20MEN1KMT2A | |
| SCHEMBL6442098 | 0.78 | ZDHHC20 (0.39) | ZDHHC20MEN1KMT2A | |
| SCHEMBL6446464 | 0.76 | OPRM1 (0.38) | KMT2A | |
| SCHEMBL6446460 | 0.76 | OPRM1 (0.38) | KMT2A | |
| SCHEMBL6822576 | 0.75 | LTB4R (0.43) | KMT2A | |
| Maleic Acid SCHEMBL10975200 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL7537527 | 0.61 | CHRM2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |