SCHEMBL6447196

SCHEMBL6447196

O=C1CCCC(=O)C1C(=O)c1ccc(Cl)c(NC(=O)N2CCOCC2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 3/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC6A3 Q01959 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.38
TP53 P04637 1/20 0.37
ESR2 Q92731 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6449902 0.81 ITGB1 (0.33) MAPTCYP2C9CYP2C19RAB9AKDM4E
SCHEMBL2902825 0.78 HPD (0.36) LMNA
SCHEMBL2905370 0.78 DRD1 (0.31) GAASMN1; SMN2TP53
SCHEMBL6448378 0.78 DRD1 (0.30)
SCHEMBL10376030 0.72 HPD (0.42)
SCHEMBL6449853 0.72 PKM (0.41) RAB9AMEN1KMT2ASLC6A3
SCHEMBL6558204 0.71 P2RX7 (0.45)
SCHEMBL6903439 0.70 P2RX7 (0.35)
SCHEMBL11197955 0.65 MEN1 (0.73) MAPTCYP2C9CYP2C19GAANPC1
SCHEMBL22946330 0.64 CYP2A13 (0.45) MAPTPOLBGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US disclosed
EP-1423009-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP disclosed
WO-2003017766-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2003-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 MAPT 3927/4885POLB 3325/4885CYP2C9 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.