SCHEMBL6449853

SCHEMBL6449853

CON(C)C(=O)Nc1c(Cl)ccc(C(=O)C2C(=O)CCCC2=O)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
SLC6A3 Q01959 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HPD P32754 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2902825 0.82 HPD (0.36) HPD
SCHEMBL3436992 0.74 SLC6A3 (0.33) SLC6A3HPD
SCHEMBL10376030 0.73 HPD (0.42) HPD
SCHEMBL6449902 0.73 ITGB1 (0.33) RAB9AMEN1KMT2AHPD
SCHEMBL2905370 0.73 DRD1 (0.31) HPD
SCHEMBL6447196 0.72 MAPT (0.42) RAB9AMEN1KMT2ASLC6A3
SCHEMBL6558204 0.72 P2RX7 (0.45)
SCHEMBL6448378 0.72 DRD1 (0.30)
SCHEMBL7041998 0.71 HPD (0.34) HPD
SCHEMBL6448509 0.70 PKM (0.39) PKMRAB9AMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 PKM 253/4885RAB9A 3694/4885MEN1 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.