Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210718 | 0.87 | MAPK1 (0.64) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL13210531 | 0.86 | RAB9A (0.67) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL30834320 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AKDM4ENPC1P4HTM | |
| SCHEMBL13210581 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9AKDM4ENPC1P4HTM | |
| SCHEMBL24891951 | 0.85 | MAPK1 (0.62) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL30182827 | 0.85 | MAPK1 (0.62) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL6450288 | 0.84 | ALDH1A1 (0.84) | ALDH1A1RAB9AKDM4ENPC1P4HTM | |
| SCHEMBL600512 | 0.81 | MAPK1 (0.74) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL13210524 | 0.81 | KDM4E (0.62) | ALDH1A1RAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL2835923 | 0.80 | PTPN1 (0.81) | ALDH1A1RAB9ANPC1L3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606338-A1 | A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS | SigmaKalon B.V. (NL) | 2005-12-21 | — | — | EP | disclosed |
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-30 | — | — | US | disclosed |
| WO-2004085518-A1 | A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS | SIGMAKALON B.V. (NL) | 2004-10-07 | — | — | WO | disclosed |
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 212/4885RAB9A 1792/4885KDM4E 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.