Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447328 | 0.94 | FFAR1 (0.48) | FFAR1PTGDR2MMP2MMP12CYP2C9 | |
| SCHEMBL6447485 | 0.88 | FFAR1 (0.43) | FFAR1PTGDR2MMP2MMP12CYP2C9 | |
| SCHEMBL6446075 | 0.80 | FFAR1 (0.50) | FFAR1PTGDR2MMP2MMP12ALOX15 | |
| SCHEMBL75765 | 0.73 | PTGDR2 (0.51) | FFAR1PTGDR2MMP2MMP12CYP2C9 | |
| SCHEMBL30852830 | 0.70 | MMP2 (0.55) | FFAR1MMP2MMP12ALOX15KDM4E | |
| SCHEMBL3634841 | 0.69 | HTT (0.58) | FFAR1MMP2MMP12CYP2C9KDM4E | |
| SCHEMBL14514021 | 0.69 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL1778144 | 0.69 | FFAR1 (0.71) | FFAR1PTGDR2ALOX15ALDH1A1 | |
| SCHEMBL96139 | 0.68 | CYP1A2 (0.58) | FFAR1CYP2C9KDM4EALDH1A1CYP1A2 | |
| SCHEMBL4683194 | 0.67 | FFAR1 (0.57) | FFAR1PTGDR2CYP2C9ALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554272-A1 | BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE | ELI LILLY AND COMPANY (US) | 2005-07-20 | — | — | EP | claimed |
| WO-2004014900-A1 | BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE | ELI LILLY AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
| US-6960588-B1 | Tryptase inhibitors | ALTANA PHARMA AG (DE) | 2005-11-01 | — | — | US | disclosed |
| EP-1216236-A1 | TRYPTASE INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019809-A1 | TRYPTASE INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-03-22 | — | — | WO | disclosed |