Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446075 | 0.91 | FFAR1 (0.50) | PTGDR2MMP2MMP12FFAR1ALDH1A1 | |
| SCHEMBL10362542 | 0.82 | LMNA (0.49) | PTGDR2MMP2MMP12EGLN1MEN1 | |
| SCHEMBL17555048 | 0.79 | LMNA (0.43) | PTGDR2MMP2MMP12EGLN1MEN1 | |
| SCHEMBL6447328 | 0.78 | FFAR1 (0.48) | PTGDR2MMP2MMP12FFAR1ALDH1A1 | |
| SCHEMBL25199212 | 0.77 | PTGDR2 (0.46) | PTGDR2MMP2MMP12EGLN1FFAR1 | |
| SCHEMBL7420788 | 0.75 | MMP2 (0.40) | MMP2MMP12FFAR1ALDH1A1KDM4E | |
| SCHEMBL12468934 | 0.75 | CYP1A2 (0.46) | PTGDR2EGLN1MEN1KMT2ALMNA | |
| SCHEMBL75802 | 0.75 | CYP2D6 (0.45) | PTGDR2EGLN1MEN1KMT2ALMNA | |
| SCHEMBL11111469 | 0.74 | ALDH1A1 (0.41) | PTGDR2EGLN1MEN1KMT2ALMNA | |
| SCHEMBL11111466 | 0.74 | ALDH1A1 (0.41) | PTGDR2EGLN1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919857-B1 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| US-8129560-B2 | Process for the synthesis of mandipropamid and derivatives thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090118532-A1 | Process for the Synthesis of Mandipropamid and Derivatives Thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-07 | — | — | US | disclosed |
| US-7166746-B2 | N-bisaryl- and n-aryl-cycloakylidenyl-αhydroxy-and α-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. | 2005-11-03 | — | — | US | disclosed |
| EP-1534664-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | Syngenta Participations AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004011417-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | CBR3, CBR1, AKR1C3 | PTGDR2 2076/4885MMP2 2284/4885MMP12 2568/4885 |
| US-20090118532-A1 | Process for the Synthesis of Mandipropamid and Derivatives Thereof | OPRM1, OPRD1, ADRA1D | PTGDR2 231/4885MMP2 469/4885MMP12 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.