Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76698 | 0.83 | LTA4H (0.50) | LTA4HTSHRKDM4EGLAMAPT | |
| Water SCHEMBL27530954 | 0.81 | LTA4H (0.48) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL28770243 | 0.81 | LTA4H (0.48) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL8126838 | 0.79 | LMNA (0.52) | LTA4HSMN1; SMN2LMNAHTT | |
| SCHEMBL8535180 | 0.79 | LTA4H (0.52) | LTA4HTSHRKMT2A | |
| SCHEMBL152163 | 0.78 | LTA4H (0.32) | LTA4HTSHR | |
| SCHEMBL1220986 | 0.76 | LTA4H (0.54) | LTA4HKMT2ALMNASLC6A2SLC6A3 | |
| SCHEMBL1930820 | 0.76 | LTA4H (0.32) | LTA4HTSHR | |
| SCHEMBL1532042 | 0.76 | ALDH1A1 (0.39) | LTA4HKDM4EMAPTKMT2ALMNA | |
| SCHEMBL2090470 | 0.76 | LTA4H (0.54) | LTA4HSMN1; SMN2MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228974-A | Ethylene oligomerization becomes the oligomerization process of the mixture of 1-hexene and 1-octene | SASOL TECH PTY LTD | 2016-01-06 | — | — | CN | disclosed |
| EP-2875014-A2 | ANTI-MUCUS DRUGS AND USES THEREFOR | Washington University (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014015056-A2 | ANTI-MUCUS DRUGS AND USES THEREFOR | WASHINGTON UNIVERSITY (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-1244359-B1 | COMBINATION OF FLUAZURON AND IVERMECTIN FOR PARASITE CONTROL | NOVARTIS AG (CH) | 2005-01-12 | — | — | EP | disclosed |
| US-6469067-B1 | FOR TREATMENT OF LIVESTOCK FOR PARASITES; COMPRISES 1-(4-CHLORO-3-(3-CHLORO-5-TRIFLUOROMETHYL-2-PYRIDYLOXY) PHENYL)-3-(2,6-DIFLUOROBENZOYL)UREA AND ONE OF: IVERMECTIN, DORAMECTIN, MOXIDECTIN AND SELAMECTIN | NOVARTIS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| EP-1244359-A1 | COMBINATION OF N-PHENYL-N'-BENZOYL UREA DERIVATIVE AND NECTIN COMPOUNDS FOR PARASITE CONTROL | Novartis AG (CH) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001037667-A1 | COMBINATION OF N-PHENYL-N'-BENZOYL UREA DERIVATIVE AND NECTIN COMPOUNDS FOR PARASITE CONTROL | NOVARTIS AG (CH) | 2001-05-31 | — | — | WO | disclosed |