Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6445368 | 0.94 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6906083 | 0.82 | PNMT (0.33) | PNMTNPC1RAB9A | |
| Ethane SCHEMBL8832631 | 0.79 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7549004 | 0.78 | PNMT (0.37) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7177315 | 0.76 | PNMT (0.30) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6445067 | 0.75 | PNMT (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7553835 | 0.73 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6471201 | 0.71 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL618215 | 0.71 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29479988 | 0.71 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065018-A1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | (1) REPSOL QUIMICA S.A. | 2005-03-24 | — | — | US | disclosed |
| EP-0953580-B1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | REPSOL QUIMICA SA (ES) | 2004-04-14 | — | — | EP | disclosed |
| US-20030144135-A1 | PREPARATION AND USE OF HETEROGENEOUS CATALYST COMPONENTS FOR OLEFINS POLYMERIZATION | REPSOL QUIMICA S.A. (ES) | 2003-07-31 | — | — | US | disclosed |
| EP-0955306-B1 | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA SA (ES) | 2003-01-22 | — | — | EP | disclosed |
| US-6114555-A | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 2000-09-05 | — | — | US | disclosed |
| EP-0955306-A1 | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 1999-11-10 | — | — | EP | disclosed |
| EP-0953580-A1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | REPSOL QUIMICA S.A. (ES) | 1999-11-03 | — | — | EP | disclosed |