Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453074 | 0.83 | AGTR1 (0.43) | HPGDSMN1; SMN2PPARAAGTR1AGTR2 | |
| SCHEMBL6454862 | 0.79 | AGTR1 (0.38) | RORCAGTR1AGTR2PPARGKDM4E | |
| SCHEMBL6450132 | 0.74 | KDM4E (0.40) | HPGDSMN1; SMN2AGTR1AGTR2KDM4E | |
| SCHEMBL25420820 | 0.68 | CYP1A2 (0.36) | HPGDSMN1; SMN2PPARGUSP2ALDH1A1 | |
| SCHEMBL30461655 | 0.68 | CYP1A2 (0.36) | HPGDSMN1; SMN2PPARGUSP2ALDH1A1 | |
| SCHEMBL19896418 | 0.66 | SIGMAR1 (0.37) | SMN1; SMN2PPARAPPARGKDM4EUSP2 | |
| SCHEMBL6451041 | 0.64 | AGTR1 (0.46) | AGTR1AGTR2PPARGKDM4EABCC3 | |
| SCHEMBL4795198 | 0.63 | TLR7 (0.33) | HPGDSMN1; SMN2 | |
| SCHEMBL23633170 | 0.63 | RAB9A (0.39) | SMN1; SMN2PPARGUSP2ALDH1A1CYP3A4 | |
| SCHEMBL17433479 | 0.61 | MTNR1A (0.38) | SMN1; SMN2PPARAPPARGALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020654-A1 | Novel PPAR agonists, pharmaceutical compositions and uses thereof | BETHESDA PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | disclosed |
| WO-2004082621-A2 | NOVEL PPAR AGONISTS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BETHESDA PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020654-A1 | Novel PPAR agonists, pharmaceutical compositions and uses thereof | PPARG, PPARD, PPARA | HPGD 1290/4885SMN1; SMN2 4764/4885RORC 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.