Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440976 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1TRPM4CYP1A2SMN1; SMN2 | |
| SCHEMBL6445463 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDCYP1A2SMN1; SMN2 | |
| SCHEMBL6442084 | 0.77 | CA2 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL6445432 | 0.71 | HSD17B10 (0.41) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6441756 | 0.71 | AR (0.43) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL17537056 | 0.70 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDCYP1A2MEN1 | |
| SCHEMBL31442188 | 0.69 | CA1 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL9751705 | 0.69 | KCNN4 (0.38) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30312307 | 0.69 | GAA (0.56) | KDM4EALDH1A1HPGDCYP1A2MEN1 | |
| SCHEMBL6232041 | 0.69 | GAA (0.56) | KDM4EALDH1A1HPGDCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893444-B1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-5936102-A | CYCLOCONDENSING O-(2-BROMOTETRAFLUOROETHOXY)PHENOL IN THE PRESENCE OF ACID BINDER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |
| EP-0893444-A1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | BAYER AG (DE) | 1999-01-27 | — | — | EP | disclosed |