SCHEMBL6232041

SCHEMBL6232041

COc1cc2ccccc2cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
NPC1 O15118 1/20 0.56
HSP90AA1 P07900 1/20 0.56
RAB9A P51151 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NQO1 P15559 1/20 0.56
KDM4E B2RXH2 6/20 0.55
ALDH1A1 P00352 4/20 0.55
HPGD P15428 3/20 0.55
CA1 P00915 3/20 0.54
TP53 P04637 2/20 0.54
CA2 P00918 1/20 0.54
TSHR P16473 1/20 0.54
CDK5 Q00535 2/20 0.53
CDK5R1 Q15078 2/20 0.53
MAPT P10636 5/20 0.50
RECQL P46063 4/20 0.50
MCL1 Q07820 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30312307 1.00 GAA (0.56) GAAMEN1KMT2ANPC1HSP90AA1
SCHEMBL30459979 0.83 NQO1 (0.68) KMT2ANPC1RAB9AL3MBTL1NQO1
SCHEMBL441442 0.83 NQO1 (0.68) KMT2ANPC1RAB9AL3MBTL1NQO1
SCHEMBL10236581 0.83 KDM4E (0.43) GAAMEN1KMT2ANPC1HSP90AA1
SCHEMBL17912881 0.81 MAOB (0.61) GAAMEN1KMT2ANPC1HSP90AA1
SCHEMBL9622898 0.81 MAOB (0.61) GAAMEN1KMT2ANPC1HSP90AA1
SCHEMBL6759689 0.78 NQO1 (0.62) KMT2ANPC1RAB9AL3MBTL1NQO1
SCHEMBL6891370 0.78 NQO1 (0.62) KMT2ANPC1RAB9AL3MBTL1NQO1
SCHEMBL11494800 0.78 ALDH1A1 (0.67) GAAMEN1KMT2ANPC1HSP90AA1
SCHEMBL69624 0.77 MAOB (0.59) MEN1KMT2ARAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2025-01-30 US claimed
CN-118055962-A Epoxy curing agent composition comprising naphthol and naphthol derivative 赢创运营有限公司 2024-05-17 CN claimed
WO-2023057234-A9 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2024-05-10 WO claimed
WO-2023057234-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2023-04-13 WO claimed
CN-114874153-A Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2022-08-09 CN claimed
CN-108654587-B Process for preparing halogenated hydrocarbons 中国石油化工股份有限公司 2021-09-07 CN claimed
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same EXXONMOBIL CHEMICAL PATENTS INC. 2018-10-04 US claimed
US-20180014547-A1 USES OF DALDINIA SP. OR VOLATILE ORGANIC COMPOUNDS DERIVED THEREFROM THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2018-01-18 US claimed
WO-2016125153-A1 USES OF DALDINIA SP. OR VOLATILE ORGANIC COMPOUNDS DERIVED THEREFROM THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2016-08-11 WO claimed
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2025-01-30 US disclosed
US-12187681-B2 Ion channel antagonists/blockers and uses thereof SHANGHAI EAST HOSPITAL (CN) 2025-01-07 US disclosed
US-12098362-B2 Uses of Daldinia sp. or volatile organic compounds derived therefrom THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2024-09-24 US disclosed
EP-4413058-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES Evonik Operations GmbH (DE) 2024-08-14 EP disclosed
CN-118055962-A Epoxy curing agent composition comprising naphthol and naphthol derivative 赢创运营有限公司 2024-05-17 CN disclosed
WO-1999006358-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-11 WO disclosed
WO-1999006356-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-11 WO disclosed
EP-0893444-A1 Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers BAYER AG (DE) 1999-01-27 EP disclosed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO disclosed
US-4341794-A ANIMAL GROWTH REGULATOR AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) 1982-07-27 US disclosed
US-4001424-A 1-Oxo-1H-naphtho [2,1-b] pyran derivatives for treating depression CARLO ERBA S.P.A. (IT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187681-B2 Ion channel antagonists/blockers and uses thereof CACNA1F, CACNA1S, CACNA1D GAA 914/4885MEN1 2638/4885KMT2A 3777/4885
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same ADH1A, ADH1C, GK GAA 608/4885MEN1 3044/4885KMT2A 1381/4885
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES SRM, PNMT, NIT2 GAA 1643/4885MEN1 1390/4885KMT2A 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.