Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449438 | 0.87 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6450699 | 0.86 | TUBB4A (0.62) | PTGS2PTGS1TUBB4ATUBBTUBA3C | |
| SCHEMBL918369 | 0.85 | CXCL12 (0.50) | MKNK2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6453166 | 0.85 | CYP1A2 (0.58) | PTGS2PTGS1TUBB4ATUBBTUBA3C | |
| SCHEMBL6449511 | 0.85 | CXCL12 (0.50) | MKNK2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6453084 | 0.83 | NFE2L2 (0.60) | PTGS2PTGS1TUBB4ATUBBTUBA3C | |
| SCHEMBL6448335 | 0.81 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL9111920 | 0.80 | TNFRSF1A (0.64) | — | |
| SCHEMBL9111913 | 0.80 | TNFRSF1A (0.64) | — | |
| SCHEMBL14157110 | 0.78 | CYP1A2 (0.72) | MKNK2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |