Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690932 | 0.70 | HRH3 (0.47) | L3MBTL3L3MBTL1MBTD1HRH3NPY2R | |
| SCHEMBL6247173 | 0.69 | AR (0.46) | ACHEL3MBTL1CYP2C19MEN1MAPT | |
| SCHEMBL411118 | 0.65 | GFER (0.46) | GAAERN1CYP2C19POLBALDH1A1 | |
| SCHEMBL12084945 | 0.64 | MEN1 (0.52) | L3MBTL1KDM4EERN1ALDH1A1MEN1 | |
| SCHEMBL406932 | 0.63 | AR (0.43) | ERN1CYP2C19POLBALDH1A1MEN1 | |
| SCHEMBL14528873 | 0.62 | L3MBTL1 (0.45) | SIGMAR1L3MBTL3L3MBTL1MBTD1GAA | |
| SCHEMBL24254398 | 0.60 | KDM4E (0.49) | KDM4EERN1ALDH1A1MEN1MAPT | |
| SCHEMBL11214658 | 0.60 | ERN1 (0.47) | KDM4EERN1ALDH1A1MEN1MAPT | |
| SCHEMBL6773381 | 0.60 | ALDH1A1 (0.54) | KDM4EERN1BRD4TSHRALDH1A1 | |
| SCHEMBL4145248 | 0.59 | GRIN2B (0.51) | HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |