Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378633 | 0.82 | SLC7A5 (0.55) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1064811 | 0.81 | EPHX2 (0.79) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL11954386 | 0.80 | CHRM2 (0.58) | KMT2AMEN1HDAC1 | |
| SCHEMBL11441079 | 0.80 | ALDH1A1 (0.63) | KMT2AALDH1A1MEN1HPGDNPC1 | |
| SCHEMBL29481931 | 0.79 | MEN1 (0.61) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL17151448 | 0.79 | MEN1 (0.61) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9545043 | 0.79 | KMT2A (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2HPGD | |
| Methylamine SCHEMBL15743165 | 0.79 | SLC7A5 (0.56) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1065668 | 0.79 | ATM (0.70) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL11432326 | 0.77 | ALDH1A1 (0.60) | KMT2AALDH1A1MEN1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119375-B2 | Method for the production of ramipril | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-1966118-B1 | IMPROVED METHOD FOR THE PRODUCTION OF RAMIPRIL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1966118-A1 | IMPROVED METHOD FOR THE PRODUCTION OF RAMIPRIL | Sanofi-Aventis Deutschland GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007079871-A1 | IMPROVED METHOD FOR THE PRODUCTION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | REN, PDE8B, PDE3A | EPHX2 1533/4885KMT2A 2722/4885ALDH1A1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.